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CELF1 PROTEIN
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DeCS
Descriptor
English
:
CELF1 Protein
Descriptor
Spanish
:
Proteínas CELF1
Descriptor
Portuguese
:
Proteínas CELF1
Tree Number:
D12.776.157.725.813.250.500
D12.776.664.962.813.250.500
Definition
English
:
A member of the
CELF PROTEINS
family
which binds GU rich
elements
(GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich
elements
(AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with
MYOTONIC DYSTROPHY
type 1.
History Note
English
:
2016
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55989
Unique Identifier:
D000067879
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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